David Breslow

David Breslow is an Associate Professor of Molecular, Cellular & Developmental Biology on Term in the Department of BIO at Yale University. He joined the Yale MCDB faculty in January 2017. Breslow received an A.B. in Biochemical Sciences from Harvard University and completed his graduate work at the University of California, San Francisco in Dr. Jonathan Weissman’s lab. There, he developed functional genomic tools for budding yeast and defined the function of Orm family proteins in sphingolipid homeostasis. As a postdoctoral fellow, he worked with Dr. Maxence Nachury at Stanford University, where he used in vitro and CRISPR-based screening approaches to study primary cilia. His research focuses on the regulation and functions of the mammalian primary cilium, including its role in signaling pathways and disease states. He is also interested in developing new functional genomic screening approaches to study cilia biology.

David K Breslow is a researcher at Yale University whose work focuses on primary cilia, functional genomics, signaling, cell cycle regulation, and centriole biology. His research explores the molecular mechanisms underlying ciliary function and dysfunction, with a particular emphasis on the role of signaling pathways in ciliogenesis and ciliopathies. Breslow's studies also investigate sphingolipid homeostasis and its connection to cellular signaling, as well as the role of Rab34 GTPase in ciliary membrane formation. His work employs advanced techniques such as CRISPR-based screens and single-molecule imaging to uncover the molecular architecture of cilia and their involvement in disease.