Gyun Min Lee

Prof. Gyun Min Lee is a Professor in the Department of BIO at KAIST. Their research focuses on bioengineering, specifically the development of therapeutic protein production using recombinant Chinese hamster ovary (CHO) cells. The ACE Lab, led by Prof. Lee, explores molecular biology and bioprocess engineering to enhance recombinant protein production. Their work includes genome-wide CRISPR screening to identify genes that improve cell resistance to environmental stressors and enhance productivity in cell lines such as HEK293T and CHO cells. Prof. Lee's research has been published in journals such as Metabolic Engineering and ACS Synthetic Biology.

Gyun Min Lee is a Professor of Biological Sciences at KAIST, specializing in biotechnology and cellular biology. Their research focuses on optimizing recombinant protein production in Chinese hamster ovary (CHO) cells, with an emphasis on factors such as culture temperature, pH, and genetic engineering. They investigate how these variables influence productivity, transcription levels, and cellular heterogeneity. Additionally, Lee explores the role of angiopoietin proteins in angiogenesis, including their interactions with Tie receptors and their potential therapeutic applications. Their work also addresses the stability and clonal variability of gene-amplified CHO cells, as well as strategies for enhancing therapeutic protein production through cell engineering.