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Stacy Malaker

Yale University · Chemistry
Chemical Biology Physical Chemistry Analytical Chemistry Biophysical Chemistry

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Stacy Malaker is an Associate Professor of Chemistry at Yale University, affiliated with the Department of Chemistry. Her research focuses on Chemical Biology, Biophysical Chemistry, Physical Chemistry, and Analytical Chemistry. Her laboratory develops methods for mass spectrometry analysis of mucin-domain glycoproteins, with an emphasis on their role in diseases such as cancer, cystic fibrosis, and inflammatory bowel disease. Malaker's work integrates expertise in mass spectrometry, chemical biology, and glycobiology to address challenges in glycoproteomics. She is also recognized for her contributions to the field through various awards and publications.


Scholar profile summary
Scholar-generated biography

Stacy A. Malaker is an associate professor at Yale University, specializing in mass spectrometry, glycobiology, mucins, and glycoproteomics. Her research focuses on the structural and functional analysis of glycoproteins, particularly mucins, and their roles in disease and immunity. Malaker's work explores how glycans modify small RNAs, influence immune responses, and impact host-commensal interactions. She develops novel methods for glycopeptide analysis and mucin-selective proteolysis to uncover posttranslational modifications and their implications in cancer and immunology. Her studies also investigate the interplay between glycan-binding receptors and immune checkpoints, contributing to understanding antigen presentation and therapeutic targeting.

Source: google_scholar · 94 words
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