Lynette Cegelski

Lynette Cegelski is the Monroe E. Spaght Professor of Chemistry and Professor, by courtesy, of Chemical Engineering at Stanford University's Department of Chemistry. Her research focuses on the Chemistry-Biology Interface and Physical Chemistry, with an emphasis on understanding complex biological systems and their organization. Her work explores the development of new methods and tools to study biological assemblies, including the use of small molecules, fluorescence and electron microscopy, and spectroscopy. She is particularly known for her research on bacterial biofilm formation and the discovery of phosphoethanolamine (pEtN) cellulose. Prior to joining Stanford in 2008, she completed her postdoctoral training at Washington University School of Medicine and earned her Ph.D. from Washington University.

Lynette Cegelski is a researcher whose work focuses on the molecular mechanisms underlying bacterial survival and pathogenesis. Her research explores the role of bacterial cell wall composition, biofilm formation, and amyloid biogenesis in antibiotic resistance and virulence. She investigates how small-molecule inhibitors can disrupt bacterial processes such as biofilm formation and cell-wall synthesis, offering new therapeutic strategies. Her studies also examine the structural and functional properties of bacterial extracellular matrices and their interactions with antibiotics. Cegelski's work bridges microbiology, biochemistry, and materials science, with a focus on understanding how bacterial physiology influences antimicrobial efficacy.