Chang Hyeshik

Chang Hyeshik is an Assistant Professor in the Department of BIO at Seoul National University. His research focuses on developing new experimental methods and data analysis techniques to enhance understanding of molecular phenomena in genomic, transcriptomic, and proteomic levels. His work includes tracking the RNA life cycle using nanopore direct RNA sequencing and high-throughput profiling of poly(A) tails. He is affiliated with the Laboratory of Quantitative Molecular Biology and maintains a website at https://qbio.io/. His email is hyeshik@snu.ac.kr.

Hyeshik Chang is a researcher at Seoul National University with expertise in post-transcriptional regulation, RNA modification, and high-throughput sequencing. His work explores the molecular mechanisms governing RNA processing, including the role of RNA modifications in gene expression and viral interactions. Chang's research includes the development of novel sequencing technologies such as TAIL-seq and mTAIL-seq to study poly(A) tail dynamics and 3′ end modifications. His studies also focus on the biogenesis of microRNAs and the functional roles of uridylation in mRNA degradation and stability. Additionally, he investigates the impact of RNA modifications on viral RNA processing and host-virus interactions, particularly in the context of SARS-CoV-2 and human cytomegalovirus.