Justin Benesch

Justin Benesch is Professor of Biophysical Chemistry in the Department of Chemistry at the University of Oxford. His research focuses on developing experimental methodologies to gain quantitative insights into protein states and structures, integrating data with computational strategies to uncover physico-chemical determinants of biomolecular function. His work explores structural and dynamical heterogeneity in proteins, the role of physico-chemical pressures in protein evolution, and the behavior of proteins under stress conditions. He is also interested in molecular chaperones, particularly Small Heat-Shock Proteins, and their interactions. Benesch obtained his PhD from the University of Cambridge and was appointed to faculty at the University of Oxford in 2012. He is also a Tutorial Fellow in Physical Chemistry at University College Oxford.

Justin Benesch is a Professor of Biophysical Chemistry at the University of Oxford, specializing in the application of mass spectrometry and ion mobility techniques to study the structure and dynamics of biological macromolecules. His research focuses on understanding the structural and functional properties of protein complexes, particularly in the context of structural proteomics and structural genomics. Benesch's work includes the analysis of large protein assemblies, the characterization of polydispersity in chaperone proteins, and the development of methodologies for quantitative mass imaging and collisional activation of protein complexes. His research has significant implications for understanding the mechanisms of protein folding, aggregation, and disease-related processes.