Regular biography
Elizabeth Marie Nolan is a Professor of Immunology at the Massachusetts Institute of Technology, affiliated with the Department of Chemistry. Her research focuses on the chemistry and biology of small molecules, peptides, and proteins involved in the human innate immune response and host/pathogen interactions, particularly in the context of infectious disease and antibiotic resistance. Her work explores the role of transition metals and metal-ion chelators in microbial pathogenesis, integrating inorganic and organic chemistry with biological chemistry and microbiology. Nolan's laboratory website provides additional details about her research and contact information.
Scholar-generated biography
Elizabeth M Nolan is a researcher in Bioinorganic Chemistry and Chemical Biology, focusing on the development of fluorescent sensors for metal ion detection in biological systems. Her work explores the role of metal ions in cellular processes and host defense mechanisms. Nolan's research includes the design of sensors for mercury, zinc, and iron, with applications in understanding metal homeostasis and pathogen interactions. She has investigated the function of host-defense proteins like calprotectin in metal sequestration and its implications for bacterial resistance. Her studies also examine the use of siderophores in antibiotic delivery and their impact on bacterial virulence.