Daniel Needleman

Daniel Needleman is a Lecturer in the Department of Molecular & Cellular Biology at Harvard University. His research combines physics and cell biology to study biological self-organizing systems, focusing on how mechanics, energetics, and molecular interactions contribute to biological organization and function. His work explores the dynamics of active matter in biological systems and seeks to develop predictive theories of biological behavior. Needleman's laboratory integrates quantitative experiments with theoretical approaches to investigate complex biological systems and their perturbations in disease and evolution. He teaches courses in experimental biological physics, quantitative cell biology, and related topics.

Daniel Needleman is a researcher in cellular biophysics and active matter, focusing on the physical mechanisms underlying cellular processes. His work explores the interplay between materials science and cell biology, particularly in the context of microtubule dynamics, spindle organization, and the role of active forces in cellular structures. Needleman's research includes the study of microtubule assembly, transport, and interactions with cytoskeletal components, as well as the physical basis of cellular organization. His publications address topics such as the regulation of glycolysis by phosphoinositide 3-kinase, the role of counterions in microtubule bundling, and the transport of lipopolysaccharide via membrane bridges. His work bridges biophysics, cell biology, and materials science to uncover the physical principles governing cellular function.