Carolyn Elya

Carolyn Elya is a Lecturer in the Department of Molecular & Cellular Biology at Harvard University. Her research focuses on host-pathogen interactions, particularly through the study of the zombie fungus Entomophthora muscae and its manipulation of Drosophila behavior. Using a multidisciplinary approach, her lab investigates molecular mechanisms underlying parasitic behavioral control, including the role of effectors, fungal cell contributions, and circadian timing of host death. The Elya lab also seeks to develop transgenic techniques in E. muscae to advance experimental access in this system. Her work has been published in journals such as Elife and IMA Fungus.

Carolyn Elya's research focuses on the mechanisms of behavioral hijacking, particularly how fungal pathogens manipulate host behavior to enhance their transmission. Her work explores the intricate interactions between fungal entomopathogens and their insect hosts, including the genetic and neural mechanisms underlying these behavioral changes. Elya's studies span various species, such as Drosophila melanogaster and Leishmania parasites, and investigate topics like host gene expression, transposon-mediated genome inflation, and the evolution of pathogenic traits. Her research also examines the role of specific genes and pathways in parasite-induced behaviors, such as summiting and altered feeding patterns. Through a combination of molecular, genetic, and behavioral approaches, Elya contributes to understanding the complex interplay between hosts and pathogens.