Evert Njomen

Evert Njomen is an Assistant Professor of Chemistry at Duke University, affiliated with the Chemistry department and the Trinity College of Arts & Sciences. His research focuses on expanding the bounds of druggability for fundamental and therapeutic discoveries through the development of covalent chemical tools and chemical proteomic technologies. His work targets proteins involved in cancers and immune disorders with unmet clinical needs, aiming to create chemical starting points for understanding biology and developing next-generation therapeutics. He is also a member of the Duke Cancer Institute.

Evert Njomen is a researcher at Duke University focusing on chemical proteomics, activity-based protein profiling, proteasome activation, proteostasis, and autophagy. His work explores therapeutic approaches targeting proteotoxic disorders through proteasome activation and small molecule modulation of proteasome assembly. He develops chemical probes to perturb protein complexes and investigates covalent inhibitors of RNA methyltransferases and other targets. His research also includes the study of cysteine allostery, STING oligomer functionality, and NLRP3 inflammasome inhibition. Njomen's contributions span from proteomic ligandability maps to the development of cell-based assays for high-throughput screening of proteasome modulators.