Regular biography
Han Xiao is a faculty member in the School of Life Sciences and Biotechnology at Shanghai Jiao Tong University. His research focuses on the biosynthesis and engineering of bioactive compounds, particularly ganoderic acids, using yeast systems. He has contributed to the decoding of biosynthetic networks and the development of efficient biosynthesis methods for valuable triterpenoids. His work includes the functional gene editing of mushrooms and the engineering of membrane-anchored cytochrome P450 enzymes. Han Xiao's research has been published in prominent journals such as Cell Discov, ACS Catal, and Nat Commun. His profile page provides additional details on his research and publications.
Scholar-generated biography
Han Xiao is a researcher specializing in metabolic engineering, synthetic biology, and genome editing. Their work focuses on developing advanced genetic tools and engineering strategies to enhance microbial production of valuable compounds. Key areas include CRISPR-Cas systems for gene disruption, metabolic pathway optimization for biofuel and terpenoid biosynthesis, and the engineering of microbial cell factories for bioproduction. Xiao's research integrates synthetic biology approaches with metabolic engineering to improve microbial tolerance and productivity, with applications in biofuel, pharmaceuticals, and biotechnology. Their studies often involve genome-scale engineering and high-throughput screening methods to accelerate the development of efficient microbial systems.