Eric Bennett

Eric Bennett is a Professor in the Department of BIO at the University of California, San Diego. His research focuses on cellular stress response and quality control pathways, particularly the ubiquitin-proteasome system (UPS) and its role in protein homeostasis. The Bennett lab investigates how dysfunction in these pathways contributes to diseases such as amyotrophic lateral sclerosis, Parkinson's disease, and cancer. His work integrates biochemical, cell biological, and systems-level approaches to understand UPS mechanisms, including the regulation of deubiquitylating enzymes (Dubs) and cullin-RING ligases (CRLs). The lab also explores global quantitative proteomic analysis of UPS function and its implications for cellular and tissue health.

Eric Bennett is a Professor at the University of California, San Diego, specializing in molecular biology and protein homeostasis. His research focuses on understanding the ubiquitin-proteasome system, deubiquitinating enzymes, and the role of ubiquitylation in cellular processes such as stress granule dynamics, ribosome-associated quality control, and disease mechanisms like Huntington's disease. Bennett's work also explores the interplay between ubiquitylation and other post-translational modifications, including N-terminal acetylation and SUMOylation, to uncover how these modifications regulate proteome complexity and cellular responses to stress. His studies aim to elucidate the molecular mechanisms underlying protein homeostasis and its disruption in neurodegenerative diseases and immune responses.