Alex Chaim

Alex Chaim is an Assistant Professor in the Department of BIO at the University of California, San Diego. His research focuses on DNA and RNA damage and repair in cellular homeostasis, neurodegeneration, and cancer. The Chaim Lab aims to establish novel molecular knowledge and methodologies to explore the molecular basis of nucleic acid damage and its role in disease. His work includes investigating inter-individual differences in DNA repair capacity and developing tools to measure these differences. Chaim has contributed to studies on oxidative DNA damage repair, RNA-binding protein interactions, and the impact of nucleic acid damage on neurodegenerative diseases and cancer treatment.

Isaac Alexander Chaim is an Assistant Professor whose research focuses on DNA repair mechanisms and their implications in disease. His work explores the role of DNA repair pathways in cancer resistance, oxidative DNA damage, and neurodegeneration. He investigates inter-individual variation in DNA repair capacity, particularly through the analysis of DNA glycosylases, APE1, and BER pathways. His studies also examine the impact of RNA damage and repair processes in neurodegenerative conditions. Chaim's research includes the development of novel assays for DNA repair and the use of cortical organoids to model early brain development and neurodegenerative disorders.