Xiaoyu Zhang

Xiaoyu Zhang is an Assistant Professor in the Department of Chemistry at Northwestern University. Her research focuses on chemical biology approaches to expand the druggable proteome of human cells and discover chemical probes for previously inaccessible protein targets. Her work includes developing chemical tools for targeted protein degradation, novel modalities for immunological pathways, and expanding the druggable landscape of the cell surface proteome. She is affiliated with multiple interdisciplinary institutes at Northwestern University, including the Chemistry of Life Processes Institute and the International Institute for Nanotechnology.

Xiaoyu Zhang is a researcher in Chemical Biology and Chemoproteomics at Northwestern University. Their work focuses on understanding the role of post-translational modifications, particularly lipidation and fatty acylation, in cellular processes. Zhang's research explores how these modifications regulate protein function, signaling pathways, and disease mechanisms. They investigate the development of chemical tools to modulate these modifications, including PROTACs and small-molecule inhibitors, to target disease-related proteins. Their studies span from elucidating the biological functions of lipidation to designing strategies for targeted protein degradation. Zhang's research has significant implications for cancer and inflammatory diseases.