Stefani Spranger

Stefani Spranger is an Associate Professor of Biology and Intramural Faculty at the Koch Institute, Massachusetts Institute of Technology. She studies how the immune system interacts with tumors to develop cancer immunotherapies. Her research uses tumor mouse models to examine the co-evolution of anti-tumor immune responses and cancer. Spranger's work focuses on understanding immune-tumor interactions to improve immunotherapies. She is affiliated with the Department of Biology at MIT and maintains a profile page at https://biology.mit.edu/profile/stefani-spranger/.

Stefani Spranger is a researcher at the Massachusetts Institute of Technology specializing in immunobiology and cancer immunology. Her work explores mechanisms by which tumors evade immune responses and how immunotherapeutic strategies can overcome these barriers. She investigates the role of signaling pathways, such as WNT/β-catenin, in tumor immune evasion and the impact of the tumor microenvironment on immune cell function. Her research also focuses on the interplay between innate and adaptive immunity in cancer immunotherapy, including the role of dendritic cells, T cells, and cytokines like IL-2. Spranger's studies contribute to understanding how immunogenic tumors can be targeted through therapies that restore immune responses.