Regular biography
Francisco J. Sánchez-Rivera is a Fellow at the Massachusetts Institute of Technology, affiliated with the Department of Biology. He serves as an Intramural Faculty member at the Koch Institute. His research focuses on understanding how genetic variation influences normal physiology and disease, particularly in cancer. His laboratory develops and applies genome engineering technologies, genetically-engineered mouse models, and single cell lineage tracing to study disease evolution. He is also recognized as the Eisen and Chang Career Development Professor.
Scholar-generated biography
Francisco J Sánchez-Rivera is a researcher at the Massachusetts Institute of Technology, focusing on Cancer Genetics, Functional Genomics, Mouse Models, and Genome Editing. His work explores the genetic and molecular mechanisms underlying cancer progression, with an emphasis on identifying therapeutic targets through advanced genomic tools. He has published extensively on topics such as CRISPR-Cas9 applications in cancer biology, genome editing in tumor models, and the role of host factors in viral infections like SARS-CoV-2. His research also investigates the interplay between tumor suppressor pathways, such as p53, and cancer cell metabolism, as well as the development of novel therapeutic strategies targeting epigenetic regulators in pancreatic cancer.