Kristin Knouse

Kristin Knouse is an Assistant Professor of Biology at the Massachusetts Institute of Technology, affiliated with the Koch Institute for Integrative Cancer Research. Her research focuses on understanding how tissues sense and respond to damage, with a particular emphasis on the mammalian liver's regenerative capacity. She develops innovative genetic, molecular, and cellular tools to study and modulate organ injury and repair within living organisms. Knouse's work aims to identify molecular requirements for effective organ repair and has contributed to advancements in genome-scale CRISPR screening and the study of chromosome segregation fidelity. She is also recognized for her role in exploring the role of aneuploidy in tissue regeneration and disease.

Kristin Knouse is a researcher at the Massachusetts Institute of Technology, focusing on Functional Genomics, Cell Biology, and Regenerative Medicine. Her work explores the mechanisms of chromosome segregation, aneuploidy, and their implications in tissue regeneration and disease. She investigates how cellular processes such as centromere maintenance, immune system interactions, and tissue architecture influence genomic stability. Her research includes single-cell sequencing, CRISPR screening, and in vivo models to understand the role of genomic instability in cancer and regenerative contexts. Knouse's studies highlight the interplay between genomic integrity and cellular function, with applications in regenerative medicine and cancer biology.