Olivia Corradin

Olivia Corradin is an Assistant Professor of Biology at the Massachusetts Institute of Technology, affiliated with the Department of Biology and the Whitehead Institute. Her research focuses on genetic and epigenetic variation that contributes to human disease by disrupting gene expression programs. She investigates the impact of disease-associated variants on cellular function and aims to identify actionable insights into disease pathogenesis by studying the interplay of genetic and epigenetic risk factors in conditions such as multiple sclerosis and opioid use disorder. Corradin's work includes analyzing physical interactions between genetic variants within chromatin regulatory circuitry and exploring the role of gene dysregulation in opioid overdose.

Olivia Corradin's research focuses on genetics, genomics, epigenetics, GWAS, and enhancers, with an emphasis on understanding how genetic and epigenetic factors contribute to complex diseases. Her work explores the role of enhancer variants in gene expression and disease susceptibility, particularly in conditions such as colon cancer, opioid addiction, and neurodegenerative disorders. Corradin investigates the functional impact of genetic variants within chromatin regulatory circuits and their interactions with epigenetic modifications. She also examines the transcriptional and epigenetic mechanisms underlying neurological conditions like autism and multiple sclerosis. Her research integrates multi-omic approaches to uncover the molecular basis of disease risk and cellular function.