Eliezer Calo

Eliezer Calo is an Associate Professor of Biology at the Massachusetts Institute of Technology. His research focuses on the molecular entities controlling RNA metabolism, including processes such as protein synthesis, processing, modifications, export, translation, and degradation. His work explores how these processes contribute to development and how mutations in RNA metabolic components lead to congenital disorders and cancer. Calo's laboratory investigates the role of RNA metabolism in tissue-specific developmental disorders and cancer, with a particular emphasis on ribosome biogenesis. His research has been published in prominent journals such as Nature and Cell.

Eliezer Calo is an Associate Professor of Biology at the Massachusetts Institute of Technology, specializing in RNA Metabolism, Ribosome Biogenesis, Ribosomopathies, and Cancer. His research explores the molecular mechanisms underlying RNA processing, particularly focusing on how RNA helicases like DDX21 coordinate transcription and ribosomal RNA processing. Calo's work also investigates the role of the retinoblastoma protein (Rb) in regulating cell fate and lineage commitment, as well as the impact of nucleolar stress and rDNA damage in developmental disorders. His studies highlight the interplay between RNA metabolism and cancer progression, with a focus on how RNA-binding proteins and glycoRNAs influence cellular processes and disease.