Regular biography
Alberto Bartesaghi is an Associate Professor of Computer Science and Associate Professor of Biochemistry (Joint) at Duke University. He is affiliated with the Computer Science department and his research focuses on cryo-electron microscopy and related computational methods. His work includes the development of platforms for single-particle cryo-ET, automated specimen evaluation, and high-resolution tomography. His research has contributed to the determination of structures of various proteins and complexes, including β-galactosidase and CRISPR-Cas surveillance complexes. His website provides further details on his research and team.
Scholar-generated biography
Alberto Bartesaghi, PhD, is a researcher specializing in Image Processing and Analysis and Cryo-Electron Microscopy. His work focuses on advancing cryo-EM techniques to achieve high-resolution structural insights into biological macromolecules. He has contributed significantly to understanding the molecular architecture of viral proteins, such as HIV-1 gp120 trimers and trimeric HIV-1 envelope glycoproteins, as well as structural mechanisms of proteins like β-galactosidase and human rhodopsin. His research also addresses computational challenges in cryo-EM, including classification and 3D averaging in electron tomography. His studies have implications for drug discovery and understanding viral entry mechanisms.