Pamela Chang

Pamela Chang is an Associate Professor in the Department of Chemistry and Chemical Biology at Cornell University. Her research focuses on developing chemical tools to understand the immune system and probe the gut microbiome, a complex community of microorganisms that influences human health and disease. Her lab employs interdisciplinary approaches, including chemical biology, microbiology, and immunology, to investigate the interactions between the gut microbiota and the host immune system. Specific research areas include the development of activity-based probes to study microbial metabolism, characterization of small-molecule metabolites that regulate inflammation, and the creation of chemical tools to modulate immune responses. Her work has implications for the development of therapeutics for inflammatory diseases.

Pamela V. Chang is an Associate Professor in Microbiology & Immunology and Chemistry & Chemical Biology at Cornell University. Her research focuses on chemical biology, microbiome, microbiology, and immunology, with an emphasis on understanding host-microbe interactions through chemical and metabolic approaches. Her work explores how microbial metabolites influence immune responses and gut barrier function, utilizing techniques such as metabolic labeling, bioorthogonal chemistry, and chemoproteomic profiling. Chang's research also investigates the role of glycans and their interactions with host receptors, as well as the development of chemical tools for imaging and analyzing biological systems. Her studies aim to uncover the molecular mechanisms underlying microbial contributions to health and disease.