En Cai

En Cai is an Assistant Professor in the Department of Biological Sciences at Carnegie Mellon University. Their research focuses on T-cell signaling and activation, cancer immunotherapy, and advanced imaging techniques such as lattice light-sheet microscopy, single molecule fluorescence microscopy, and super-resolution imaging. Dr. Cai's work includes studies on synaptic transfer of tumor antigens among dendritic cells and dynamic microvillar search and stabilization during ligand detection by T cells. They are affiliated with the Mellon College of Science and can be contacted via email at encai@andrew.cmu.edu or their lab website at https://www.cmu.edu/bio/people/faculty/cai.html.

En Cai is a researcher at Carnegie Mellon University specializing in immunology and super-resolution imaging. Their work focuses on visualizing dynamic processes in immune cell interactions, such as the co-dependency between macrophages and exhausted CD8+ T cells in cancer, and the mechanisms of T cell microvilli contacts during ligand detection. Cai's research also explores synaptic transfer of tumor antigens among dendritic cells and the use of quantum dots for high-resolution imaging. They have contributed to advancements in super-resolution techniques, including the development of stable small quantum dots for synaptic receptor tracking and fluorescence imaging with one-nanometer accuracy. Their studies aim to enhance understanding of immune cell dynamics at the nanoscale.