Regular biography
Professor Gonçalo Bernardes is a Professor of Chemical Biology in the Yusuf Hamied Department of Chemistry at the University of Cambridge. He is also a Fellow of Trinity Hall College. His research focuses on developing chemical reactions to modify proteins with precision, aiming to create therapeutic benefits. His work includes selectively labelling proteins in living cells and linking cytotoxic drugs to antibodies for targeted cancer treatments. He is funded by the Royal Society, UKRI, and the European Commission. His research group's website provides further details on their work.
Scholar-generated biography
Gonçalo Bernardes is a researcher in Chemical Biology with a focus on Protein Modification, Antibody-drug Conjugates, and Vaccines. His work explores innovative chemical strategies for site-selective protein modification, enabling advancements in drug development and functional material design. He has contributed to the development of methods for cysteine modification, including the conversion of cysteine to dehydroalanine, and has investigated the use of carbon monoxide-releasing molecules for therapeutic applications. His research also includes the design of mimics for cytokines like IL-2 and IL-15, as well as the synthesis of materials for environmental remediation. Bernardes' work bridges chemical synthesis with biological applications, emphasizing precision and functionality in molecular design.