Regular biography
Dr Katie Bentley is a Reader in Computer Science in the Department of Informatics at King’s College London. She is also a Group Leader of the Cellular Adaptive Behaviour Lab at the Francis Crick Institute. Her research focuses on developing agent-based simulations and other computational methods to model individual to collective cell behaviour during the growth of well-adapted structures in embryo development and abnormal, maladapted structures in diseases such as cancer and retinopathy. Her research interests include simulation of adaptive behaviour, computational biology, bio-inspired robotics, artificial life, software engineering of biological models, cell and developmental biology, blood vessel formation, eye disease, and Vaccinia Virus spread.
Scholar-generated biography
Katie Bentley is a computational biologist whose research focuses on vascular biology, adaptive systems, and artificial life. Her work explores the dynamic processes underlying angiogenesis, including endothelial cell behavior, tip cell selection, and vascular patterning. Bentley employs computational models and experimental approaches to study how signaling pathways such as Notch and VEGFR regulate vascular development and disease. She has developed agent-based models, such as OpenABM-Covid19, to simulate biological systems and assess non-pharmaceutical interventions. Her research also investigates the role of molecular mechanisms, such as glycolytic regulation and acetylation, in vascular morphogenesis and disease progression.