Paul N Barlow

Professor Paul N Barlow is a member of the Chemistry department at The University of Edinburgh. His research focuses on protein structure, nuclear magnetic resonance spectroscopy, immunology, and the complement system. His work explores the complement system's role in autoimmune and inflammatory diseases, with an emphasis on understanding the structural and functional mechanisms of complement proteins. He has contributed to the structural analysis of complement regulatory proteins, such as factor H, and has developed methods for recombinant protein expression and biophysical characterization. His research integrates techniques like NMR, FRET, and EPR to study protein interactions and dynamics.

Paul N Barlow is a Professor of Structural Biology at Edinburgh University, specializing in proteins, immunology, structural biology, and the complement system. His research focuses on understanding the molecular mechanisms of protein interactions, particularly in the context of immune responses and complement regulation. Barlow's work includes elucidating the structural basis of complement factor H interactions, the role of the complement system in diseases, and the structural dynamics of proteins involved in immune recognition. His studies have contributed to understanding the molecular architecture of proteins such as factor H, complement receptor 1, and MDM2, with implications for diseases like age-related macular degeneration and atypical hemolytic uremic syndrome.