David J. Clarke

Prof David Clarke is the Chair of Mass Spectrometry at the University of Edinburgh, School of Chemistry. His research focuses on developing and applying mass spectrometry techniques to study complex biomolecules and biological systems. His work includes advancing methods such as isotope-depletion mass spectrometry (ID-MS), which enhances analytical sensitivity for protein analysis. His research has applications in drug discovery, vaccine design, and synthetic biology, with collaborations with industrial partners. Prof Clarke's expertise spans mass spectrometry, protein characterization, and biomolecular analysis, with a focus on molecular characterization of complex chemical and biological systems.

David J. Clarke is a Professor of Mass Spectrometry at the University of Edinburgh, specializing in Mass Spectrometry, Protein Chemistry, Enzymology, and Structural Biology. His research focuses on understanding the structural and functional properties of proteins and enzymes through advanced mass spectrometry techniques. Clarke's work explores the molecular mechanisms of protein interactions, enzyme inhibition, and structural conversions, with applications in antimicrobial activity, neurodegenerative diseases, and immune responses. His studies also address the chemical complexity of natural products and the structural characterization of biomolecules using top-down and middle-down mass spectrometry approaches. His research contributes to the fields of structural biology, biochemistry, and analytical chemistry.