Regular biography
L. P. McIntosh is a researcher with a strong focus on structural biology, particularly in the areas of NMR spectroscopy and enzyme mechanisms. Their work has spanned a wide range of topics, including the structural characterization of enzymes, the role of phosphorylation in transcription factor function, and the use of NMR to study protein dynamics and interactions. McIntosh has contributed significantly to the understanding of glycoside hydrolases, sialyltransferases, and other enzymes involved in carbohydrate metabolism. They have also explored the use of NMR to study phosphoserine and phosphothreonine residues, as well as the electrostatic interactions in enzyme active sites. Their research has been published in numerous high-impact journals, including *Journal of Biological Chemistry*, *Biochemistry*, and *Proteins: Structure, Function, and Bioinformatics*. McIntosh has collaborated with many researchers in the field of structural biology and has been involved in both academic and industrial projects, including work on protein secretion chaperones and glycosynthase-based synthesis of oligosaccharides. Overall, their research has provided important insights into the molecular mechanisms of enzyme action and protein function.