Yi XUE

Yi XUE is an Associate Professor in the School of Life Sciences at Tsinghua University. His research focuses on characterizing the structure and dynamics of non-coding RNAs and intrinsically disordered proteins using solution NMR spectroscopy and computational methods such as MD simulations. His work aims to develop novel NMR techniques, labeling methods, and computational tools to study the three-dimensional structure and conformational switches of large non-coding RNAs and ribonucleoproteins. He has published extensively in top-tier journals, including Nature Communications and Science Bulletin, and has contributed to antiviral drug design and structural insights into biomolecular interactions.

Yi Xue is a researcher at Tsinghua University with a focus on structural and dynamic studies of biomolecules. Their work explores the structural and dynamic basis of molecular interactions, including DNA and RNA dynamics, protein conformational changes, and the role of post-translational modifications in epigenetic regulation. Key areas of interest include NMR spectroscopy, DNA repair mechanisms, and the structural basis of protein-ligand interactions. Research also involves the study of RNA folding intermediates, tautomerization processes, and the impact of NADPH levels on epigenetic states. Their publications highlight the use of advanced NMR techniques to investigate molecular dynamics and conformational exchange processes in proteins and nucleic acids.