Wanli LIU

Wanli Liu is a Professor in the School of Life Sciences at Tsinghua University. He earned his Ph.D. in Biological Science and Biotechnology from Tsinghua University and completed postdoctoral training at the University of California, San Francisco, and the National Institute of Allergy and Infectious Diseases, National Institutes of Health. His research focuses on the molecular mechanisms of B-cell antigen receptor-mediated immune activation and antibody response, including the study of B lymphocyte function in autoimmune diseases, lymphatic cancers, and vaccine development. His work has been published in leading journals such as Nature, Science, and Cell.

Wanli Liu is a researcher at Tsinghua University with a focus on B cell receptor dynamics, B cell activation mechanisms, and the development of vaccines against Influenza A virus. His work explores how B cell signaling is influenced by mechanical forces and substrate stiffness, and how these factors impact antibody responses. Liu's research also investigates the role of B cell receptors in autoimmune diseases like systemic lupus erythematosus (SLE). His publications highlight the importance of antigen presentation, epitope density, and immunoglobulin isotype switching in shaping immune responses. Additionally, he has contributed to the design of bivalent influenza vaccines and explored novel therapeutic strategies for B-cell malignancies using PROTAC-induced BTK degradation.