Jun YAO

Jun YAO is a Faculty member in the School of Life Sciences at Tsinghua University. His research focuses on the pathogenesis of mood disorders, including bipolar disorder and depression, utilizing human induced pluripotent stem cells (iPSC), 3-D organoids, and mouse models. His work explores molecular, neural circuit, and genetic mechanisms underlying these conditions. Dr. Yao holds a Ph.D. from The Pennsylvania State University and has conducted postdoctoral research at the Howard Hughes Medical Institute and The Salk Institute for Biological Studies. His laboratory investigates risk factors in patient-derived neurons and organoids to understand disease mechanisms and potential therapeutic targets.

Jun Yao is a researcher at Tsinghua University with a focus on neuroscience, particularly in the areas of synaptic function, neurogenesis, and neurodevelopmental disorders. Their work explores the molecular mechanisms underlying synaptic transmission, including the roles of calcium sensors, exosomes, and synaptic vesicle dynamics. Yao's research also investigates the impact of genetic and environmental factors on neuronal plasticity and disease models, such as bipolar disorder and schizophrenia. By utilizing human pluripotent stem cells and CRISPR-based techniques, they aim to uncover the cellular and molecular bases of neurological conditions. Their studies highlight the importance of synaptic proteins, such as synaptotagmin and SV2, in neurotransmitter release and membrane trafficking.