Yang, Tianjin

Asst. Prof. Yang, Tianjin is an Assistant Professor in the School of Biological Sciences at Nanyang Technological University. His research focuses on single-molecule spectroscopy, intrinsically disordered proteins, microfluidics, chromatin dynamics, and biomolecular condensates. His work explores how molecular interactions and structural transitions regulate biological function, particularly through the study of intrinsically disordered proteins. He develops microfluidic, optofluidic, and single-molecule spectroscopy methods to capture fast, transient molecular processes with high temporal resolution. His research includes publications in Nature Methods, Nature Reviews Physics, and Analytical Chemistry.

Tianjin Yang's research focuses on the development and application of microfluidic technologies for studying biomolecular dynamics and chemical reactions. Their work includes the use of single-molecule FRET to probe nanoscale biomolecular interactions and the design of droplet-based microfluidic systems for enzyme kinetics and biomolecular assays. Yang also explores the integration of absorbance and fluorescence detection for high-sensitivity analysis in picoliter-volume droplets. Additionally, they investigate the thermodynamics of complexation between highly charged disordered proteins and the role of counterion entropy in polyelectrolyte interactions. The research emphasizes the use of microfluidics for reactive gelation, temperature-controlled reactors, and passive synchronization of droplets for kinetic studies.