Regular biography
Professor Peter Preiser is a member of the School of Biological Sciences at Nanyang Technological University. His research focuses on the molecular mechanisms used by the malaria parasite to avoid host immunity and adapt to changes in the host cell environment. Specifically, his work examines malaria merozoite recognition and penetration of the erythrocyte, identifying the Reticulocyte Binding Protein Homologues (RH) family of proteins as regulators of both merozoite and erythrocyte signaling. He also investigates the biological role of small variant antigens like the STEVOR and PIR multigene families, which play an immune modulatory role and shield infected red blood cells from immune clearance. His research also addresses drug resistance in infectious diseases, with efforts focused on developing high-sensitivity diagnostic tools and exploring new therapeutic approaches.
Scholar-generated biography
Peter Preiser is a researcher in the School of Biological Sciences at Nanyang Technological University, specializing in malaria parasite biology. His work focuses on the molecular mechanisms underlying malaria parasite infection, including the study of gene expression, protein function, and genetic variation in Plasmodium species. He has contributed significantly to understanding the transcriptomic and genomic features of malaria parasites, particularly in relation to drug resistance and host cell interaction. His research also explores the role of specific proteins, such as STEVOR, in erythrocyte invasion and antigenic variation. Additionally, he investigates the evolutionary origins and structural features of malaria parasite DNA, including plastid-like and mitochondrial DNA.