Loh, Jia Tong

Asst. Prof. Loh, Jia Tong is an Assistant Professor in the School of Biological Sciences at Nanyang Technological University. His research focuses on immunology, innate immunity, infectious diseases, and early life immunology. The Loh Lab investigates immunoregulation and immunopathogenesis during early life using preclinical mouse models to identify therapeutic targets, assess risk factors for severe infectious diseases, and develop novel vaccine adjuvants. His work aims to improve immune responses in children and reduce the need for booster shots.

Jia Tong Loh's research focuses on the molecular mechanisms underlying immune responses and their implications in infectious diseases and inflammatory conditions. Their work explores the role of epigenetic regulators, such as Ezh2, in modulating cell adhesion and migration, with implications for cancer and immune-related disorders. Loh also investigates the function of neutrophils in antifungal immunity and their contribution to diseases like rheumatoid arthritis and atopic dermatitis. Additionally, they examine the therapeutic potential of mesenchymal stromal cell exosomes in modulating immune cell polarization and reducing inflammation. Their studies highlight the interplay between host-derived lipids, gut microbiota, and immune signaling pathways in disease resistance and pathogenesis.