Koh, Cheng Gee

Assoc. Prof. Koh, Cheng Gee is an Associate Professor in the School of Biological Sciences at Nanyang Technological University. His research focuses on signal transduction in cancer biology, regulation of the actin cytoskeleton, and drug discovery in tropical medicinal plants. The Koh lab investigates the effectors and regulators of Rho GTPases, particularly kinases activated by these proteins and their interactions with phosphatases to modulate actin architecture. His work explores how these molecular mechanisms contribute to cancer cell migration and metastasis, as well as their potential in therapeutic applications.

Cheng-Gee Koh is a researcher in Cell Biology and Cancer Biology, focusing on the molecular mechanisms underlying cellular responses to mechanical cues and their implications in cancer progression. His work explores the roles of Rho GTPases, actin cytoskeleton dynamics, and phosphatases such as POPX2 in regulating cell motility, invasiveness, and apoptosis. Koh's research also investigates the interplay between signaling pathways, including the PAK-PIX and TAK1-IKK-NF-κB pathways, in cancer cell behavior. His studies contribute to understanding how mechanical forces and signaling networks influence cellular processes, with potential applications in anti-cancer therapies.