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Qiang Zhou

We are studying the mechanisms factors that control transcriptional elongation how this control affects HIV replication latency activation cancer progression

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Qiang Zhou is Professor Emeritus of Biochemistry at the University of California, Berkeley, in the Department of BIO. His research focuses on the mechanisms and factors that control transcriptional elongation and how this control affects HIV replication, latency activation, and cancer progression. Zhou's work explores the role of the positive transcription elongation factor b (P-TEFb) and its interactions with other factors in regulating gene expression and viral transcription. His research has implications for understanding and potentially treating HIV/AIDS and cancer.


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Qiang Zhou is a Professor of Molecular and Cell Biology at the University of California, Berkeley, with expertise in Biochemistry, molecular biology, and HIV virology. His research focuses on the regulation of RNA polymerase II elongation and its role in transcriptional control. Zhou's work explores the mechanisms by which transcription elongation factors, such as P-TEFb, are recruited and regulated by host and viral factors. His studies have uncovered the role of bromodomain proteins, such as Brd4, in coordinating transcriptional activation with cell cycle progression. Additionally, Zhou investigates how HIV-1 Tat interacts with host factors to modulate transcription and latency. His research has significant implications for understanding viral gene expression and transcriptional regulation in cellular processes.

Source: google_scholar · 115 words
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