Roberto Zoncu

Roberto Zoncu is a Professor of Molecular Therapeutics at the University of California, Berkeley, in the Department of BIO. His research focuses on understanding how nutrients regulate growth and homeostasis, with particular emphasis on the role of the lysosome in nutrient sensing and signaling. Zoncu's work explores how nutrient-derived signals remodel cellular processes and how these mechanisms contribute to diseases such as cancer, diabetes, and neurodegeneration. His laboratory employs advanced live cell microscopy, biochemical assays, and high-throughput profiling to investigate the molecular mechanisms underlying metabolic regulation. Zoncu's research also addresses the inter-organelle communication in metabolic control and the development of novel chemical tools to manipulate nutrient signaling pathways.

Roberto Zoncu is a researcher in Cell Biology and Cancer Biology, focusing on the molecular mechanisms that regulate cellular growth, metabolism, and disease. His work explores the role of mTORC1 in integrating growth signals, amino acid sensing, and lysosomal function. Zoncu's research also investigates the interplay between lysosomes, autophagy, and transcriptional regulation in cancer metabolism. His studies highlight the importance of lysosomal signaling pathways in disease progression and cellular homeostasis. Additionally, he examines the role of lipid metabolism and mitochondrial function in cellular stress responses. His contributions provide insights into the molecular basis of cancer and metabolic disorders.