Regular biography
Professor Eric Alton holds the Chair in Gene Therapy at Imperial College London's Department of Bioengineering. His research focuses on gene therapy, though specific details are not provided. He is affiliated with the university and maintains a profile page at https://profiles.imperial.ac.uk/e.alton. No further information on his academic background, awards, or publications is available.
Scholar-generated biography
Eric WFW Alton is a Professor of Gene Therapy and Respiratory Medicine specializing in cystic fibrosis (CF) and gene therapy. His research focuses on developing non-viral and viral gene delivery methods to correct the CFTR gene defect in patients with cystic fibrosis. Alton's work includes liposome-mediated and Sendai virus-based gene transfer techniques to restore ion transport in airway epithelium. He has conducted clinical trials evaluating the safety and efficacy of gene therapy in CF patients, emphasizing the importance of reducing inflammation and achieving sustained pulmonary gene expression. His research also explores the pathophysiology of CF lung disease and novel approaches to gene delivery, such as magnetic nanoparticle-based systems.