Regular biography
Dr Charis Pericleous is a Research Fellow at Imperial College London, affiliated with the BIO department. Their research interests and specific contributions are not detailed in the available information. Dr Pericleous' profile page indicates a focus on computational biology and data science, though further details are not provided. Their work is accessible via the Imperial College London profiles website.
Scholar-generated biography
Charis Pericleous is a researcher at the NHLI, Imperial College London, focusing on the antiphospholipid syndrome (APS) and its pathogenic mechanisms. Her work explores how antiphospholipid antibodies interact with β2-glycoprotein I, influencing inflammatory responses and thrombosis. She investigates the role of these antibodies in modulating trophoblast function, angiogenic factors, and monocyte signaling pathways, with implications for pregnancy complications and vascular disease. Pericleous also examines the therapeutic potential of hydroxychloroquine and the use of novel assays to detect molecular oxidative modifications of β2-glycoprotein I. Her research bridges immunology, molecular biology, and clinical medicine to improve diagnostic and therapeutic strategies for APS.