Sarah A. Stanley

Sarah A. Stanley is an Associate Professor of Immunology and Molecular Medicine at the University of California, Berkeley, in the Department of BIO. Her research focuses on innate and adaptive immune responses to Mycobacterium tuberculosis, a bacterial pathogen responsible for tuberculosis. Stanley's work explores how Mtb evades and suppresses immune responses, contributing to the global burden of the disease. Her lab investigates the mechanisms of immune resistance and the potential for developing new vaccines and therapeutics. Stanley's research also examines bacterial virulence factors that enable Mtb to counteract host immunity. She is the Richard and Rhoda Goldman Distinguished Chair and maintains a lab homepage at https://www.thestanleylab.org/.

Sarah Stanley, affiliated with UC Berkeley, focuses on tuberculosis host-pathogen interactions. Her research explores the mechanisms by which Mycobacterium tuberculosis subverts host immune responses, particularly through specialized secretion systems and the role of Type I IFN in pathogenesis. She investigates how host factors like HIF-1α and IFN-γ influence immune defenses against tuberculosis and identifies potential therapeutic targets through high-throughput screening. Her work also extends to understanding lipid droplet formation and the role of STING-activating adjuvants in combating infection. Stanley's research contributes to the development of novel inhibitors targeting bacterial virulence factors and host-pathogen interactions during tuberculosis and related viral infections.