Max Staller

Max Staller is an Assistant Professor in Residence of Genetics at the University of California, Berkeley, within the Department of BIO. His research focuses on transcriptional regulation, particularly the mechanisms of transcription factors that activate transcription. He investigates DNA binding domains and activation domains, which are essential for development, stress responses, and homeostasis. Staller's work explores how activation domains, which are intrinsically disordered and poorly conserved, function and evolve. His lab employs high-throughput experiments, machine learning, and evolutionary comparisons to study these domains and predict their properties from protein sequences. His research also includes characterizing variants of uncertain significance in activation domains associated with autism spectrum disorder.

Max V. Staller is a researcher at the University of California, Berkeley, specializing in Systems Biology and Gene Regulation & Development. His work focuses on understanding the molecular mechanisms of gene regulation, particularly through the study of transcriptional activation domains. Staller's research explores how mutations in these domains affect gene expression and how they contribute to developmental processes. His studies include the functional characterization of activation domains in various organisms, such as Drosophila and plants, and the identification of key residues that influence transcriptional activity. He also investigates the evolutionary conservation of these domains and their role in genetic variation. His research has implications for understanding gene regulation in development and disease.