Regular biography
Eva Nogales is a Professor of Biochemistry at the University of California, Berkeley, in the Department of BIO. Her research focuses on understanding crucial molecular processes in eukaryotic cells, particularly cytoskeletal dynamics in cell division and the molecular mechanisms governing genetic information flow. Her work emphasizes studying macromolecular assemblies as functional units through visualization of their states and regulatory interactions. She utilizes electron microscopy, biochemical, and biophysical methods to investigate these systems. Her lab explores microtubule regulation, gene expression, and structural biology, with a focus on structural insights into molecular mechanisms.
Scholar-generated biography
Eva Nogales is a researcher at UC Berkeley and the Lawrence Berkeley National Lab, specializing in Cytoskeleton, Transcription, and Cryo-EM. Her work focuses on elucidating the structural mechanisms of microtubules and other cytoskeletal components using cryo-electron microscopy. She has contributed significantly to understanding the structural dynamics of tubulin, GTP hydrolysis, and microtubule interactions with proteins like tau. Her research also extends to CRISPR-Cas systems, including the structural insights into Cas9 and CasX enzymes. Nogales has published extensively on the structural basis of drug resistance in cancer cells and the development of cryo-EM as a powerful tool in structural biology.