Regular biography
Prof. Dr. Markus Stoffel is a Full Professor at the Department of Biology, ETH Zurich. His research focuses on Metabolism and Metabolic Diseases, with an emphasis on understanding the molecular mechanisms that regulate glucose and lipid metabolism. His work explores transcriptional and microRNA regulatory networks in pancreatic β-cells, liver, fat, and hypothalamus, particularly in response to physiological and environmental stress. The integration of extracellular hormonal and nutrient signals into gene expression patterns is central to his research, aiming to elucidate the role of genetic and genomic regulation in maintaining glucose and lipid homeostasis.
Scholar-generated biography
Markus Stoffel is a researcher at ETH Zurich with expertise in Metabolism, Diabetes, RNA biology, and RNA therapeutics. His work explores the role of microRNAs in metabolic regulation and disease, including their impact on insulin secretion, glucose metabolism, and diabetes. He has investigated the therapeutic potential of RNA-based interventions, such as antagomirs, to modulate microRNA activity. His research also addresses the molecular mechanisms underlying genetic forms of diabetes, such as mutations in glucokinase and AKT2. Stoffel's contributions highlight the interplay between RNA biology and metabolic disorders, offering insights into novel therapeutic strategies.