Michael Marletta

Michael Marletta is a Professor of Biochemistry at the University of California, Berkeley, affiliated with the Department of Molecular and Cell Biology. His research focuses on the intersection of chemistry and biology, particularly in understanding protein function and enzyme reaction mechanisms. His work explores molecular answers to complex biological functions, including nitric oxide signaling and gas sensing in prokaryotes and eukaryotes. Current projects involve the study of molecular mechanisms of polysaccharide monooxygenases and their role in cellulose degradation. His laboratory has contributed to understanding the structure and function of enzymes involved in nitric oxide signaling, including the discovery of H-NOX proteins and their role in biological sensing.

Michael A. Marletta is a Professor of Chemistry and Biochemistry at the University of California, Berkeley, with research focused on protein structure/function, particularly in the context of nitric oxide (NO) biology. His work explores the mechanisms of nitric oxide synthase (NOS), including its structure, catalytic activity, and role in cellular signaling. He has also investigated the biochemical pathways of nitrite and nitrate production in macrophages and the function of soluble guanylate cyclase in NO/cGMP signaling. His research integrates enzymology, biochemistry, and molecular biology to elucidate the biochemical basis of NO-mediated physiological processes.