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Thomas Mann

Our lab’s interests are at the intersection of signal transduction differentiate into many specialized states. However antigen exposure isn’t a one-time experience T cells in all differen

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Thomas Mann is an Assistant Professor of Immunology and Molecular Medicine in the Department of Molecular and Cell Biology at the University of California, Berkeley. His research focuses on the intersection of signal transduction and T cell differentiation, particularly in the context of antigen recognition and T cell exhaustion during cancer and chronic viral infection. His lab investigates how antigen signals influence T cell differentiation and how differentiation states regulate T cell signaling responses. Mann's work aims to develop new immunotherapies by understanding the molecular mechanisms underlying T cell fate and function. His research has been published in prominent journals, including Science and Nature Immunology.


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Thomas H. Mann, affiliated with the University of California Berkeley, focuses on signal transduction, cell fate, and T cells. His research explores the molecular mechanisms governing cell fate decisions, particularly in immune cells such as T cells, and how signaling pathways influence cellular responses. His work includes studies on T cell exhaustion, the role of histone modifications in cell fate regulation, and the spatial organization of cell cycle modules. Mann's contributions also extend to RNA structure prediction and the development of standardized methods for RNA chemical mapping. His research bridges molecular biology, immunology, and systems biology to understand how cellular processes are regulated.

Source: google_scholar · 103 words
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