Meng-meng Fu

Meng-meng Fu is an Assistant Professor of Cell Biology in the Department of Molecular and Cell Biology at the University of California, Berkeley. Her research focuses on glial function at the animal, cell, and molecular levels to elucidate mechanisms of normal development and disease progression. Her lab investigates the role of Golgi outposts in acentrosomal microtubule nucleation in oligodendrocytes and the partner proteins that work with the microtubule nucleator TPPP to organize microtubules. Additionally, her work explores mRNA transport in oligodendrocytes and its importance in myelination, as well as mechanisms of leukodystrophies, cytoskeletal organization in astrocytes, and blood-brain barrier failure in vascular dementia.

Meng-meng Fu's research focuses on Cell Biology, Neuroscience, Glia, and Oligodendrocytes, with an emphasis on understanding the molecular mechanisms underlying myelination and axonal transport. Her work explores how cytoskeletal dynamics, motor proteins, and RNA trafficking contribute to the development and maintenance of myelin sheaths. Key areas include the role of scaffolding proteins like JIP1 in regulating motor-driven transport, the function of Golgi outposts in microtubule nucleation, and the impact of mRNA transport defects on neurological disorders. Fu's studies also investigate the interplay between glial cells and neurons in myelin formation and repair, particularly in the context of leukodystrophies and schizophrenia.