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John G. Flannery

Molecular Biology which afflict 1 in 3000 people worldwide arise primarily from mutations in transcripts expressed in rod cone photoreceptors

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John G. Flannery is a Professor of Molecular Therapeutics in the Department of Molecular and Cell Biology at the University of California, Berkeley. His research focuses on molecular biology and gene therapies for inherited retinal degenerations, particularly those affecting photoreceptor cells and retinal pigment epithelial cells. His work involves understanding the genetic and mechanistic basis of photoreceptor degeneration and developing rational therapies for these conditions. Flannery's laboratory develops animal models of inherited retinal diseases and explores viral-mediated gene therapies for both autosomal dominant and recessive retinal degenerations. His research also addresses challenges in gene delivery technologies for retinal gene therapy.


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John Gerard Flannery is a Professor at the University of California, Berkeley, specializing in retina neuroscience and gene therapy. His research focuses on developing gene delivery methods for retinal diseases, particularly through adeno-associated virus (AAV) vectors. He investigates strategies to enhance transduction efficiency and target specific retinal cells, such as photoreceptors and Müller cells. His work also explores the role of gene therapy in treating inherited retinal degenerations, including the use of ribozymes and neurotrophic factors to slow photoreceptor loss. Flannery's studies contribute to understanding the molecular mechanisms underlying retinal disorders and advancing therapeutic interventions.

Source: google_scholar · 95 words
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