Regular biography
Markus Jeschek is a Tenure Track Assistant Professor in the Department of CHEM at École Polytechnique Fédérale de Lausanne. His research focuses on synthetic and applied microbiology, with an emphasis on sustainable biosynthesis. Jeschek is affiliated with the Laboratory of Synthetic and Applied Microbiology (LSAM1) and holds the Lonza Chair in Sustainable Biosynthesis. He is also associated with the SCGC - Teaching program at EPFL. His work includes interdisciplinary chemical biology and microbiology to address societal challenges such as climate change and resource scarcity.
Scholar-generated biography
Markus Jeschek is a professor at the Swiss Federal Technology Institute of Lausanne (EPFL) whose research focuses on the development of artificial metalloenzymes and biocatalytic systems for sustainable chemical synthesis. His work integrates synthetic biology, directed evolution, and machine learning to engineer enzymes capable of performing novel reactions, such as metathesis and radical biocatalysis. Jeschek's research also explores combinatorial pathway optimization, metabolic engineering, and DNA-based phenotypic recording to enhance biocatalytic efficiency and reduce experimental effort. His contributions span from the design of chemo-enzymatic cascades to the creation of biotin-independent strains for improved streptavidin production.