Carlos Bustamante

Carlos Bustamante is a Professor of Biochemistry at the University of California, Berkeley, affiliated with the Department of BIO. His research focuses on the development and application of single-molecule manipulation and detection techniques, including Optical Tweezers, Single Molecule Fluorescence microscopy, and Scanning Force Microscopy. His work explores the behavior of DNA-binding molecular motors, the mechanical unfolding of proteins and RNA, and the structural properties of chromatin and protein-nucleic acid complexes. Bustamante's laboratory investigates the molecular mechanisms of gene regulation, transcription, and recombination in prokaryotes, as well as the mechanochemical properties of molecular motors such as the bacteriophage phi 29 connector and FtsK.

Carlos Jose Bustamante, a researcher at the University of California, Berkeley, specializes in Single Molecule Biophysics. His work explores the mechanical properties of biological molecules, including DNA and RNA, using techniques such as optical tweezers and magnetic beads. His research focuses on understanding the elasticity, folding, and unfolding mechanisms of nucleic acids and proteins at the single-molecule level. Bustamante's studies have contributed significantly to the field of single-molecule mechanics, particularly in elucidating the behavior of DNA under tension and the thermodynamics of molecular folding. His research has also examined the role of ionic effects on DNA elasticity and the application of fluctuation theorems in nonequilibrium systems.