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David Bilder

Epithelial Architecture: Polarity Tumor Suppression Morphogenesis Research in my laboratory focuses on the biology of epithelia the fundamental tissue of all animals the major constituent of human organs. We study the molecules mechanisms that govern epithelial polarity cell shape tissue morphogenesis

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David Bilder is a Professor of Cell Biology in the Department of BIO at the University of California, Berkeley. His research focuses on epithelial architecture, including polarity, tumor suppression, and morphogenesis. His laboratory uses Drosophila as a model system to study the molecular and mechanistic basis of epithelial organization, tissue morphogenesis, and the relationship between epithelial structure and tumorigenesis. His work explores how epithelial polarity regulates organ growth and how disruptions in this organization contribute to cancer progression. Additionally, he investigates the biological mechanisms by which tumors affect host physiology, including processes such as cachexia and host mortality.


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David Bilder is a Professor of Molecular & Cell Biology at UC-Berkeley, specializing in the study of epithelial polarity, tumor suppression, and developmental biology. His research focuses on the molecular mechanisms underlying cell polarity, proliferation control, and tissue homeostasis, primarily using the model organism Drosophila. Bilder investigates how tumor suppressor genes regulate epithelial growth and prevent neoplastic transformation, with an emphasis on the role of PDZ proteins, endocytic pathways, and Notch signaling. His work also explores the interplay between cellular processes and the tumor microenvironment, including autophagy and insulin signaling in cancer progression.

Source: google_scholar · 92 words
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