Helen Bateup
Regular biography
Helen Bateup is an Associate Professor of Molecular Therapeutics in the Department of Molecular and Cell Biology at the University of California, Berkeley. Her research focuses on how neurons modulate synaptic inputs and maintain balanced excitability to support learning and prevent neurological dysfunction. She investigates the molecular mechanisms underlying neurodevelopmental disorders such as autism and epilepsy, using a multidisciplinary approach that includes molecular, biochemical, and electrophysiological techniques in mouse models and human stem cell-derived brain organoids. Her work explores the role of genetic mutations in altering neural development and function, with a particular emphasis on the mTOR pathway and its involvement in disorders like Tuberous Sclerosis Complex.
Scholar-generated biography
Helen S. Bateup is a neurobiologist at the University of California, Berkeley, whose research focuses on the molecular and circuit mechanisms underlying motivated behavior, synaptic plasticity, and neural disorders. Her work explores how dopamine and other neurotransmitter systems regulate neural circuits in the striatum and nucleus accumbens, with implications for understanding psychiatric and neurological conditions. Bateup's research integrates molecular, cellular, and systems approaches to study the role of gene expression, signaling pathways, and neural connectivity in health and disease. Her studies span topics such as tuberous sclerosis, autism spectrum disorders, and the development of human neural organoids as models for neurodevelopmental disorders.